Diagnostic Pathology: Molecular Oncology, 2nd Edition

by Mohammad A. Vasef, MD

Covering all aspects of molecular pathology as it relates to the transformation and pathogenesis of cancer, this award-winning volume in the Diagnostic Pathology series is an expert resource for pathologists at all levels of experience and training, both as a quick reference and as an efficient review to improve knowledge and skills. This easily accessible point-of-care reference features templated, bulleted content that is generously illustrated with charts, graphs, tables, and colour photomicrographs of histology with special stains. It offers a practical, clinical approach to examining how molecular mutations affect common medical diseases and identifies the relevant and appropriate molecular tests to perform for a complete work-up in the era of molecular-targeted therapies.

  • Provides updated information on molecular mutations in different tumours, including solid tumours and hematopoietic neoplasms, and new targeted therapies geared toward these molecular alterations


  • Discusses now widely used immunotherapy treatments, including how immunotherapy has revolutionized the treatment of many neoplasms such as breast and lung carcinomas and lymphoma


  • Features more than 2,000 annotated images throughout, including H&E stains, immunostains, and FISH images


  • Covers timely topics such as:
    • Recent advances in cancer immunotherapy, specifically in the molecular basis of immunotherapy


    • Newly discovered targeted therapies, including multiple lung carcinoma therapies now considered for patients based on existing mutations to specific genes (KRAS, ALK, BRAF, and ROS),


    • The need for integration of myeloid and lymphoid gene panels is due to increased knowledge from next-generation sequencing studies of new mutations and the resulting newly developed molecular targets


    • Increased usage of next-generation sequencing techniques 
      • Changes to hematopoietic tumour details based on revised WHO guidelines


      • Recipient of a 2016 BMA Award: Highly Commended, Pathology (previous edition)

      • An enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices


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