Description
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The Genetics and Neurobiology of Down Syndrome provides a thorough review of the genetic etiology and mechanisms of trisomy 21. The author discusses the history of the syndrome, along with its clinical features and health consequences, including physical, cognitive, and neurologic symptoms. Genetic counselling on the pros and cons of prenatal screening and testing and associated ethical issues are explored. This unique book also covers the societal and demographic aspects as well as the future direction of therapeutic development.
- Reviews genetic etiology and mechanisms of trisomy 21
- Discusses prenatal screening and genetic counselling, including ethical aspects
- Explores link between Down Syndrome and susceptibility to Alzheimer’s and early brain aging
- Covers cognitive and neurological symptoms and other health consequences
- Identifies future therapeutic developments
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